In 70% of people with Addison's disease the adrenal glands are being attacked by their bodies antibodies this means that they have an autoimmune condition.
Addison's disease is also called chronic adrenal insufficiency, primary adrenal insufficiency, primary failure adrenocortical insufficiency or hypocortisolism.
We have 2 adrenal glands, 1 above each kidney. The outer layers of the adrenal glands make hormones needed by the body - cortisol and aldosterone. The gradual destruction of the outer layers during the disease means adrenal glands do not produce enough of the hormone cortisol and, in some cases, the hormone aldosterone.
The disease was named after Thomas Addison who described patients with this disorder in 1855.
The symptoms result from the insufficient production of the hormones cortisol and aldosterone. Symptoms include:
- fatigue
- changes in skin color
- gastrointestinal problems
- low blood pressure
- dehydration
- mood changes
- increased excretion of water
- muscle pain
- loss of appetite
Diagnosis is confirmed through tests including ACTH stimulation (which measures the amount of cortisol in the blood), x-rays of the adrenal glands in the abdomen and insulin-induced hypoglycemia test.
Treatment is focused on replacing the deficient hormones.
Addison’s Disease Resources
Signs and Symptoms of Addison's Disease
Experience Project. Anonymously connect with people who share your experiences– like those who say 'I Have Addison's Disease'.
This community has been developed to offer those who have and are affected by Addison's Disease with support and information about the disease.
Addisons disease. Authoritative facts about the skin from the New Zealand Dermatological Society.
Addison's Disease | Overview -- FamilyDoctor.org
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Undo Learn about the symptoms, causes, diagnosis and treatment of Addison's disease, a disease that affects your body's adrenal glands.
Overview of Addison's disease and adrenal insufficiency disorders.
Addison's Disease Support. A non-profit organization providing information and support for Addison's Disease
[PDF] The website is on-line presence of the UK Addison's Disease Self Help Group (ADSHG).